LEAD DISCOVERY IN THE WEB

Iaakov Exman, Michal Pinto

2010

Abstract

The Web is a huge and very promising source of medical drug leads. But, conventional search with generic search engines, does not really obtain novel discoveries. Inspired by the drug discovery approach, we add the idea of a "lead" to the search process. The resulting Lead-&-Search protocol avoids the trap of repeated fruitless search and is domain independent. The approach is applied in practice to drug leads in the Web. To serve as input to generic search engines, multi-dimensional chemical structures are linearized into strings, which are sliced into keyword components. Search results are reordered by novelty criteria relevant to drug discovery. Case studies demonstrate the approach: linearized components produce specific search outcomes, with low risk of semantic ambiguity, facilitating reordering and filtering of results.

Paper Citation

in Harvard Style

Exman I. and Pinto M. (2010). LEAD DISCOVERY IN THE WEB . In Proceedings of the International Conference on Knowledge Discovery and Information Retrieval - Volume 1: KDIR, (IC3K 2010) ISBN 978-989-8425-28-7, pages 471-474. DOI: 10.5220/0003098304710474

in Bibtex Style

@conference{kdir10,
author={Iaakov Exman and Michal Pinto},
title={LEAD DISCOVERY IN THE WEB},
booktitle={Proceedings of the International Conference on Knowledge Discovery and Information Retrieval - Volume 1: KDIR, (IC3K 2010)},
year={2010},
pages={471-474},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003098304710474},
isbn={978-989-8425-28-7},
}

in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Knowledge Discovery and Information Retrieval - Volume 1: KDIR, (IC3K 2010)
TI - LEAD DISCOVERY IN THE WEB
SN - 978-989-8425-28-7
AU - Exman I.
AU - Pinto M.
PY - 2010
SP - 471
EP - 474
DO - 10.5220/0003098304710474