SCORING OF BREAST TISSUE MICROARRAY SPOTS THROUGH ORDINAL REGRESSION

Telmo Amaral, Stephen McKenna, Katherine Robertson, Alastair Thompson

2009

Abstract

Breast tissue microarrays (TMAs) facilitate the study of very large numbers of breast tumours in a single histological section, but their scoring by pathologists is time consuming, typically highly quantised, and not without error. This paper compares the results of different classification and ordinal regression algorithms trained to predict the scores of immunostained breast TMA spots, based on spot features obtained in previous work by the authors. Despite certain theoretical advantages, Gaussian process ordinal regression failed to achieve any clear performance gain over classification using a multi-layer perceptron. The use of the entropy of the posterior probability distribution over class labels for avoiding uncertain decisions is demonstrated.

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Paper Citation


in Harvard Style

Amaral T., McKenna S., Robertson K. and Thompson A. (2009). SCORING OF BREAST TISSUE MICROARRAY SPOTS THROUGH ORDINAL REGRESSION . In Proceedings of the Fourth International Conference on Computer Vision Theory and Applications - Volume 2: VISAPP, (VISIGRAPP 2009) ISBN 978-989-8111-69-2, pages 243-248. DOI: 10.5220/0001808202430248

in Bibtex Style

@conference{visapp09,
author={Telmo Amaral and Stephen McKenna and Katherine Robertson and Alastair Thompson},
title={SCORING OF BREAST TISSUE MICROARRAY SPOTS THROUGH ORDINAL REGRESSION},
booktitle={Proceedings of the Fourth International Conference on Computer Vision Theory and Applications - Volume 2: VISAPP, (VISIGRAPP 2009)},
year={2009},
pages={243-248},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001808202430248},
isbn={978-989-8111-69-2},
}


in EndNote Style

TY - CONF
JO - Proceedings of the Fourth International Conference on Computer Vision Theory and Applications - Volume 2: VISAPP, (VISIGRAPP 2009)
TI - SCORING OF BREAST TISSUE MICROARRAY SPOTS THROUGH ORDINAL REGRESSION
SN - 978-989-8111-69-2
AU - Amaral T.
AU - McKenna S.
AU - Robertson K.
AU - Thompson A.
PY - 2009
SP - 243
EP - 248
DO - 10.5220/0001808202430248