AUTOMATIC DETECTION OF PALE PATH AND OVERLAPS IN CHROMOSOME IMAGES USING ADAPTIVE SEARCH TECHNIQUE AND RE-THRESHOLDING

Rajeev Ranjan, Akila Subasinghe A., Jagath Samarabandu, Joan H. M. Knoll, Peter K. Rogan

2012

Abstract

Detection and separation of overlapping and touching chromosomes is a critical issue in image analysis applications for cytogenetics where accurately segmented chromosomes are essential. We present a novel method of automatic pale path detection for all types of stained chromosome images. Optimum number of cut-points for each cluster of touching or overlapping chromosomes is obtained and analysed sequentially for the pale paths. A self-adaptive search window searches for the minimum grayscale intensity beginning from the vicinity of a cut-point and propagates gradually till the end of pale path. Efficient image and area thresholding restricts the faulty detection of touch or overlap in a chromosome cluster.

Paper Citation

in Harvard Style

Ranjan R., Subasinghe A. A., Samarabandu J., H. M. Knoll J. and K. Rogan P. (2012). AUTOMATIC DETECTION OF PALE PATH AND OVERLAPS IN CHROMOSOME IMAGES USING ADAPTIVE SEARCH TECHNIQUE AND RE-THRESHOLDING . In Proceedings of the International Conference on Computer Vision Theory and Applications - Volume 1: VISAPP, (VISIGRAPP 2012) ISBN 978-989-8565-03-7, pages 462-466. DOI: 10.5220/0003862604620466

in Bibtex Style

@conference{visapp12,
author={Rajeev Ranjan and Akila Subasinghe A. and Jagath Samarabandu and Joan H. M. Knoll and Peter K. Rogan},
title={AUTOMATIC DETECTION OF PALE PATH AND OVERLAPS IN CHROMOSOME IMAGES USING ADAPTIVE SEARCH TECHNIQUE AND RE-THRESHOLDING},
booktitle={Proceedings of the International Conference on Computer Vision Theory and Applications - Volume 1: VISAPP, (VISIGRAPP 2012)},
year={2012},
pages={462-466},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003862604620466},
isbn={978-989-8565-03-7},
}

in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Computer Vision Theory and Applications - Volume 1: VISAPP, (VISIGRAPP 2012)
TI - AUTOMATIC DETECTION OF PALE PATH AND OVERLAPS IN CHROMOSOME IMAGES USING ADAPTIVE SEARCH TECHNIQUE AND RE-THRESHOLDING
SN - 978-989-8565-03-7
AU - Ranjan R.
AU - Subasinghe A. A.
AU - Samarabandu J.
AU - H. M. Knoll J.
AU - K. Rogan P.
PY - 2012
SP - 462
EP - 466
DO - 10.5220/0003862604620466