COMPUTER SIMULATION OF MICROELECTRODE BASED BIO-IMPEDANCE MEASUREMENTS WITH COMSOL

Alberto Olmo, Alberto Yúfera

2010

Abstract

Electrical models for microelectrode-cell interfaces are essential to match electrical simulations to real bio-systems performance and correctly to decode the results obtained experimentally. The accurate response simulation of a microelectrode sensor to changes in the cell-electrode system, such as cell growth, enables the optimum microelectrode design process. We report the use of COMSOL quasi-static mode, contrary to other DC modes frequently used, including magnetic fields to calculate the bioimpedance of the system. A fully electrode-cell model has been built, and the effect of fibroblasts of different diameters on the simulated impedance of small microelectrodes (32-µm square) has been studied, in order to validate the model and to characterize the microelectrode sensor response to changes in cell size and density.

Paper Citation

in Harvard Style

Olmo A. and Yúfera A. (2010). COMPUTER SIMULATION OF MICROELECTRODE BASED BIO-IMPEDANCE MEASUREMENTS WITH COMSOL . In Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010) ISBN 978-989-674-017-7, pages 178-182. DOI: 10.5220/0002740301780182

in Bibtex Style

@conference{biodevices10,
author={Alberto Olmo and Alberto Yúfera},
title={COMPUTER SIMULATION OF MICROELECTRODE BASED BIO-IMPEDANCE MEASUREMENTS WITH COMSOL},
booktitle={Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)},
year={2010},
pages={178-182},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002740301780182},
isbn={978-989-674-017-7},
}

in EndNote Style

TY - CONF
JO - Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)
TI - COMPUTER SIMULATION OF MICROELECTRODE BASED BIO-IMPEDANCE MEASUREMENTS WITH COMSOL
SN - 978-989-674-017-7
AU - Olmo A.
AU - Yúfera A.
PY - 2010
SP - 178
EP - 182
DO - 10.5220/0002740301780182