TOWARDS PERSONALIZED DRUG DELIVERY - Preparation of an Encapsulated Multicompartment System

Maik Hadorn, Peter Eggenberger Hotz

2010

Abstract

Single liposomes and vesicles are successfully utilized as delivery vehicles of pharmaceuticals. However limitations of these unilamellar, single compartments led to the development of encapsulated multicompartment systems that establishes the prospect of multicomponent or multifunctional drug delivery systems. So far compartmentalization is restricted to binary systems. To realize a personalized drug delivery, a programmable linkage of n-entities of different content will be needed. Here we present both a programmable DNA-mediated linkage of three distinct vesicle populations and a novel encapsulation protocol. We discuss how the techniques established in this study might be used in personalized healthcare based on custom-tailored encapsulated multicompartment vesicular drug delivery systems.

Paper Citation

in Harvard Style

Hadorn M. and Eggenberger Hotz P. (2010). TOWARDS PERSONALIZED DRUG DELIVERY - Preparation of an Encapsulated Multicompartment System . In Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010) ISBN 978-989-674-017-7, pages 5-12. DOI: 10.5220/0002691400050012

in Bibtex Style

@conference{biodevices10,
author={Maik Hadorn and Peter Eggenberger Hotz},
title={TOWARDS PERSONALIZED DRUG DELIVERY - Preparation of an Encapsulated Multicompartment System},
booktitle={Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)},
year={2010},
pages={5-12},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002691400050012},
isbn={978-989-674-017-7},
}

in EndNote Style

TY - CONF
JO - Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)
TI - TOWARDS PERSONALIZED DRUG DELIVERY - Preparation of an Encapsulated Multicompartment System
SN - 978-989-674-017-7
AU - Hadorn M.
AU - Eggenberger Hotz P.
PY - 2010
SP - 5
EP - 12
DO - 10.5220/0002691400050012