Multiple Source Phototherapy in Breast Cancer: A Viability Study

A. Lopes, A. Gabriel, J. Machado, P. Ribeiro, R. Gomes, João M. P. Coelho, C. O. Silva, C. P. Reis, J. P. Santos, P. Vieira

2016

Abstract

Radiation therapy is one of many common treatments applied to breast cancer. Most usual radiation sources applied are ionizing radiation, such as g-rays and X-rays, and non-ionizing radiation such as ultraviolet radiation. The possibility of using near infrared light to photoactivate a drug inside an 8 cm diameter biological object is discussed in this work via Monte Carlo simulations. Two simulation setups performed in the Geant4/GAMOS framework are presented in order to study the viability of photoactivating a drug by using several near infrared light sources. The overall objective of this technique is to minimize energy concentrated at objects surface and maximize it in a predefined region of interest. Results show an increase energy absorption in the desired region of interest inside a 8 cm object, when a higher absorption particle is present. With the use of multiple sources it is possible to photoactivate the drug while causing minimal damage to the surface of the radiated object.

Paper Citation

in Harvard Style

Lopes A., Gabriel A., Machado J., Ribeiro P., Gomes R., Coelho J., Silva C., Reis C., Santos J. and Vieira P. (2016). Multiple Source Phototherapy in Breast Cancer: A Viability Study . In Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, (BIOSTEC 2016) ISBN 978-989-758-170-0, pages 247-250. DOI: 10.5220/0005794902470250

in Bibtex Style

@conference{biodevices16,
author={A. Lopes and A. Gabriel and J. Machado and P. Ribeiro and R. Gomes and João M. P. Coelho and C. O. Silva and C. P. Reis and J. P. Santos and P. Vieira},
title={Multiple Source Phototherapy in Breast Cancer: A Viability Study},
booktitle={Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, (BIOSTEC 2016)},
year={2016},
pages={247-250},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005794902470250},
isbn={978-989-758-170-0},
}

in EndNote Style

TY - CONF
JO - Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, (BIOSTEC 2016)
TI - Multiple Source Phototherapy in Breast Cancer: A Viability Study
SN - 978-989-758-170-0
AU - Lopes A.
AU - Gabriel A.
AU - Machado J.
AU - Ribeiro P.
AU - Gomes R.
AU - Coelho J.
AU - Silva C.
AU - Reis C.
AU - Santos J.
AU - Vieira P.
PY - 2016
SP - 247
EP - 250
DO - 10.5220/0005794902470250