EVALUATION OF NOVEL ALGORITHM FOR SEARCH OF SIGNAL COMPLEXES TO DESCRIBE COMPLEX FRACTIONATED ATRIAL ELECTROGRAM

V. Kremen, L. Lhotska

2008

Abstract

Complex fractionated atrial electrograms (CFAEs) represent the electrophysiologic substrate for atrial fibrillation (AF). Progress in signal processing algorithms to identify CFAEs sites is crucial for the development of AF ablation strategies. Individual signal complexes in CFAEs reflect electrical activity of electrophysiologic substrate at given time. We developed and tested a novel algorithm based on wavelet transform. This algorithm enables to find individual signal complexes in CFAEs automatically and based on that the CFAEs complexity can be described in a novel way. The method was tested using a representative set of 1.5s A-EGMs (n = 113) ranked by an expert into 4 categories: 1 - organized atrial activity; 2 - mild; 3 - intermediate; 4 - high degree of fractionation. Individual signal complexes were marked by an expert in every A-EGM in the dataset. This ranking was used as gold standard for comparison with the novel automatic search method. Achieved results indicate that use of appropriate level of wavelet signal decomposition could carry high level of predictive information about the state of electrophysiologic substrate for AF and is efficient to help to describe the level of complexity of CFAEs in a novel way.

Paper Citation

in Harvard Style

Kremen V. and Lhotska L. (2008). EVALUATION OF NOVEL ALGORITHM FOR SEARCH OF SIGNAL COMPLEXES TO DESCRIBE COMPLEX FRACTIONATED ATRIAL ELECTROGRAM . In Proceedings of the First International Conference on Bio-inspired Systems and Signal Processing - Volume 2: BIOSIGNALS, (BIOSTEC 2008) ISBN 978-989-8111-18-0, pages 416-419. DOI: 10.5220/0001069404160419

in Bibtex Style

@conference{biosignals08,
author={V. Kremen and L. Lhotska},
title={EVALUATION OF NOVEL ALGORITHM FOR SEARCH OF SIGNAL COMPLEXES TO DESCRIBE COMPLEX FRACTIONATED ATRIAL ELECTROGRAM},
booktitle={Proceedings of the First International Conference on Bio-inspired Systems and Signal Processing - Volume 2: BIOSIGNALS, (BIOSTEC 2008)},
year={2008},
pages={416-419},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001069404160419},
isbn={978-989-8111-18-0},
}

in EndNote Style

TY - CONF
JO - Proceedings of the First International Conference on Bio-inspired Systems and Signal Processing - Volume 2: BIOSIGNALS, (BIOSTEC 2008)
TI - EVALUATION OF NOVEL ALGORITHM FOR SEARCH OF SIGNAL COMPLEXES TO DESCRIBE COMPLEX FRACTIONATED ATRIAL ELECTROGRAM
SN - 978-989-8111-18-0
AU - Kremen V.
AU - Lhotska L.
PY - 2008
SP - 416
EP - 419
DO - 10.5220/0001069404160419