THE CONSEQUENCES OF LOW FREQUENCY AND INTENSITY ELECTROMAGNETIC FIELDS ON THE FREQUENCY OF MICRONUCLEI IN HeLa CELLS

Cosmin Teodor Mihai, Gabriela Căpraru, Elena Truță, Pincu Rotinberg, Daniela Gherghel

2011

Abstract

The treatment of HeLa neoplastic cells with low frequency and intensity electromagnetic field has determined modifications of the micronuclei number, this impact being correlated with the application manner of the electromagnetic field (continuous or discontinuous). Thus, the continuous electromagnetic field has reduced the frequency of the micronuclei formation (2.91 ± 0.015 ‰), as compared to the value of control group (3.93 ± 0.023 ‰), while the discontinuously applied electromagnetic field has increased the number of micronuclei (4.92± 0.012 ‰). These variations in micronuclei number suggested that low frequency electromagnetic field interfere in different ways with the genetic material of cancerous cells, indicating that the cEMF had a protective effect upon DNA molecule, while dcEMF had a genotoxic impact. Also, the estimation of the micronuclei area has revealed that the area of micronuclei generated by dcEMF was smaller than that of cEMF.

Paper Citation

in Harvard Style

Mihai C., Căpraru G., Truță E., Rotinberg P. and Gherghel D. (2011). THE CONSEQUENCES OF LOW FREQUENCY AND INTENSITY ELECTROMAGNETIC FIELDS ON THE FREQUENCY OF MICRONUCLEI IN HeLa CELLS . In Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2011) ISBN 978-989-8425-37-9, pages 440-443. DOI: 10.5220/0003292804400443

in Bibtex Style

@conference{biodevices11,
author={Cosmin Teodor Mihai and Gabriela Căpraru and Elena Truță and Pincu Rotinberg and Daniela Gherghel},
title={THE CONSEQUENCES OF LOW FREQUENCY AND INTENSITY ELECTROMAGNETIC FIELDS ON THE FREQUENCY OF MICRONUCLEI IN HeLa CELLS},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2011)},
year={2011},
pages={440-443},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003292804400443},
isbn={978-989-8425-37-9},
}

in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2011)
TI - THE CONSEQUENCES OF LOW FREQUENCY AND INTENSITY ELECTROMAGNETIC FIELDS ON THE FREQUENCY OF MICRONUCLEI IN HeLa CELLS
SN - 978-989-8425-37-9
AU - Mihai C.
AU - Căpraru G.
AU - Truță E.
AU - Rotinberg P.
AU - Gherghel D.
PY - 2011
SP - 440
EP - 443
DO - 10.5220/0003292804400443