Automated Quantification of the Relation between Resistor-capacitor Subcircuits from an Impedance Spectrum

Thomas Schmid, Dorothee Günzel, Martin Bogdan

2014

Abstract

In epithelial physiology, it is common to use an equivalent electric circuit with two resistor-capacitor (RC) subcircuits in series as a model for the electrical behavior of body cells. The relation between these two subcircuits can be quantified by a quotient of their time constants t. While this quotient is a direct indicator of the shape of impedance spectra, its value cannot be determined directly. Here, we suggest a machine learning-based approach to predict the t quotient from impedance spectra. We perform systematic extraction of statistical features, algorithmic feature ranking and dimension reduction on model impedance spectra derived from tissue-equivalent electric circuits. Our results demonstrate that this quotient can be predicted reliably enough from implicit features to discriminate semicircular against non-semicircular impedance spectra.

Paper Citation

in Harvard Style

Schmid T., Günzel D. and Bogdan M. (2014). Automated Quantification of the Relation between Resistor-capacitor Subcircuits from an Impedance Spectrum . In Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2014) ISBN 978-989-758-011-6, pages 141-148. DOI: 10.5220/0004746501410148

in Bibtex Style

@conference{biosignals14,
author={Thomas Schmid and Dorothee Günzel and Martin Bogdan},
title={Automated Quantification of the Relation between Resistor-capacitor Subcircuits from an Impedance Spectrum},
booktitle={Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2014)},
year={2014},
pages={141-148},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004746501410148},
isbn={978-989-758-011-6},
}

in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2014)
TI - Automated Quantification of the Relation between Resistor-capacitor Subcircuits from an Impedance Spectrum
SN - 978-989-758-011-6
AU - Schmid T.
AU - Günzel D.
AU - Bogdan M.
PY - 2014
SP - 141
EP - 148
DO - 10.5220/0004746501410148