Dynamic Response of Electrocardiographic Indices During Abrupt Heart Rate Changes - Comparison between Young and Middle-aged Subjects

Marcos Javier Teperino, María Paula Bonomini, Pablo Daniel Cruces, Pedro David Arini

2015

Abstract

Abnormal modifications in ventricular repolarization dispersion (VRD) have been shown to constitute a substrate for malignant arrhythmias. In this work, we have induced abrupt heart rate (HR) changes to young and middle-aged healthy subjects through a Tilt-test and have analyzed the evolution of several VRD indices. Duration ones, based on electrocardiogram intervals; energy ones, developed through a Principal Components Analysis (PCA) in T-wave; and the morphology ones, extracted feature from an absolute T-wave. In both groups, results have shown significant decreases in early repolarization duration. These changes are responsible for the alterations in the total repolarization duration, because T-wave peak-to-end has not shown statistical significance. Moreover, we have found significant decreases in total, early and late repolarization energy, and in the T-wave amplitude. In another sense, we have observed that the repolarization energy obtained by PCA jointly with early T-wave slope and amplitude have been able to reflect VRD differences between young and middle-aged subjects. Finally, this work provides the range of values for VRD in normal conditions during abrupt HR changes. Outside this range, we could assume that it exists a cardiac risk.

Paper Citation

in Harvard Style

Javier Teperino M., Bonomini M., Cruces P. and Arini P. (2015). Dynamic Response of Electrocardiographic Indices During Abrupt Heart Rate Changes - Comparison between Young and Middle-aged Subjects . In Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2015) ISBN 978-989-758-069-7, pages 264-269. DOI: 10.5220/0005253102640269

in Bibtex Style

@conference{biosignals15,
author={Marcos Javier Teperino and María Paula Bonomini and Pablo Daniel Cruces and Pedro David Arini},
title={Dynamic Response of Electrocardiographic Indices During Abrupt Heart Rate Changes - Comparison between Young and Middle-aged Subjects},
booktitle={Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2015)},
year={2015},
pages={264-269},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005253102640269},
isbn={978-989-758-069-7},
}

in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2015)
TI - Dynamic Response of Electrocardiographic Indices During Abrupt Heart Rate Changes - Comparison between Young and Middle-aged Subjects
SN - 978-989-758-069-7
AU - Javier Teperino M.
AU - Bonomini M.
AU - Cruces P.
AU - Arini P.
PY - 2015
SP - 264
EP - 269
DO - 10.5220/0005253102640269